منابع مشابه
Second Messengers.
Second messengers are small molecules and ions that relay signals received by cell-surface receptors to effector proteins. They include a wide variety of chemical species and have diverse properties that allow them to signal within membranes (e.g., hydrophobic molecules such as lipids and lipid derivatives), within the cytosol (e.g., polar molecules such as nucleotides and ions), or between the...
متن کاملLipids as hormones and second messengers
Some lipids act as hormones to induce responses in target tissues whereas others influence the behavior of cell-surface receptors and/or serve as second messengers; i.e. they are formed as part of the cellular response to extracellular agonists, and directly affect protein kinases, ion channels and other systems that govern cell behavior. Our understanding of these functions on a structural lev...
متن کاملInositol trisphosphate and diacylglycerol as second messengers.
Hormones and neurotransmitters that use calcium as a second messenger specifically hydrolyse membrane phosphoinositides. This perturbation of membrane phospholipids may represent a fundamental transducing mechanism that initiates a signal cascade resulting in the mobilization of calcium, the activation of protein kinase C, the release of arachidonic acid (for the synthesis of prostaglandins, th...
متن کاملAldebaran M . Hofer and Konstantinos Lefkimmiatis ' ' Third Messengers ' ' ? Extracellular Calcium and cAMP : Second Messengers as
Physiol. Soc.. ESSN: 1548-9221. Visit our website at http://www.the-aps.org/. Sci./Am. American Physiological Society, 9650 Rockville Pike, Bethesda MD 20814-3991. © 2007 Int. Union Physiol. the physiological developments. It is published bimonthly in February, April, June, August, October, and December by (formerly published as News in Physiological Science) publishes brief review articles on ...
متن کاملSome Metabolites Act as Second Messengers in Yeast Chronological Aging
The concentrations of some key metabolic intermediates play essential roles in regulating the longevity of the chronologically aging yeast Saccharomyces cerevisiae. These key metabolites are detected by certain ligand-specific protein sensors that respond to concentration changes of the key metabolites by altering the efficiencies of longevity-defining cellular processes. The concentrations of ...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Biology
سال: 2016
ISSN: 1943-0264
DOI: 10.1101/cshperspect.a005926